Following the footsteps of both her parents - ace filmmaker Priyadarshan and former actress Lissy, Kalyani Priyadarshan started her career in the film industry by assisting Anand Shankar in the Nayanthara and Vikram-starrer Iru Murugan. Much before taking to the film industry, Kalyani studied at New York's Parsons School of Design. While most thought she would turn director, just like her father, she took to acting, like her mother. Making her debut, she was cast opposite Nagarjuna's younger son Akhil Akkineni in award-winning director Vikram Kumar's Telugu action romance thriller Hello! in 2017.