By Rohit Sindhu, Updated : Jul 21, 2020 19:27 IST
India is working on four vaccines, two in phase 1 and 2 off trials, NITI Aayog

According to NITI Aayog, India’s two COVID 19 vaccines are in phase 1 and 2 are off trials. VK Paul a member of NITI Aayog on Tuesday said that currently in India two of the total four vaccines are under human trials. NITI Aayog holding a press conference briefed on all proceedings going on in the country and assured that vaccine will be made available to all those who needs it. "They will not leave any stone unturned to ensure people of India and International community will have access to the Indian Vaccine as early as possible", Paul said. Every possible facilitation will be ensured making sure trials conducted scientifically &  ethically & we arrive at an affordable option. Here is an overview of COVID19 vaccines- 

1) Covaxin: Bharat Biotech developed Covaxin, India's first vaccine candidate for COVID-19, in collaboration with the Indian Council of Medical Research (ICMR) - National Institute of Virology, initiated phase 1 on July 15 2020 at post Graduate Institute of Medical Sciences in Rohtak. According to sources, AIIMS-Patna has chosen 10 volunteers to start the human trial of Covaxin. After two weeks, if the vaccine is found to be safe it will be given to more people.

2) BBV152: Human clinical trials of BBV152 COVID Vaccine or Covaxin will begin tomorrow in a special laboratory set up at the Institute of Medical Sciences and SUM (IMS & SUM) Hospital in Bhubaneswar. While human clinical trials are currently going on, Zydus CEO Pankaj Patel said that the company is hopeful of completing phase I/II study in the next few months and is trying to make it ready for use by March next year.

3) Mynvac: Third vaccine from India which is currently off trials is named as a protein based vaccine. Mynvac has been under clinical trials.

4) AstraZeneca is also hopeful of starting human trials of its vaccine in India, starting August. The vaccine, which has so far been found to be safe and effective is expected to be made available for the masses by the end of 2020. Indian Immunologicals Limited uses innovative codon-deotimization technology which directly targets cells infected by SARS.

Bharat Biotech, Serum Institute, Zydus Cadila, Panacea Biotec, Indian Immunologicals, Mynvax and Biological E are among the seven domestic pharma firms working on the coronavirus vaccines in India.

India is not lagging behind any country for the development of vaccine. UK’s Oxford-AstraZeneca, Russia, US-based Moderna, India’s COVAXIN, and Zydus Cadila, and Chinese companies including Sinovac made significant progress.  “It’s not about getting there first but to be able to do it well and it is good that India has been able to come up with candidate vaccines, which is not a small achievement.” Says T. Sundararaman, global coordinator of the People’s Hemalth Movement. “Clinical trials cannot be rushed,” says Indian virologist and veteran vaccine researcher Thekkekara Jacob John, formerly of the Christian Medical College in Vellore. “Normally, the probability of success for a vaccine in the preclinical phase is around 7%, rising to 15% to 20% for vaccines that reach clinical tests,” such as Covaxin and ZyCov-D, Berkley says.

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“I do not know about the details of this particular vaccine candidate but there are more than 200 trials happening around the world currently for developing a vaccine against Covid-19, and all are currently far from the stage of manufacturing. None of these are a ready vaccine, rather, these are merely vaccine candidates,” says minister Harsh Vardhan. “Having said that, I want to tell people that India government is in touch with all concerned involved in anti-Covid vaccine development, both nationally and internationally.

I want to assure our citizens that the government is working to ensure whenever a vaccine is ready, wherever it is ready, it will be made available to our people also. We are also in touch with the World Health Organisation in this regard. We won’t lag behind in any way. We have plans in place and at the right time, we will make the information public, Health Minister added.